Research

Periodontal condition and type 2 diabetes risk: 15-year follow-up results

22.08.18

Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterised by insulin resistance and elevated blood glucose levels, influenced by factors like obesity and inflammation.

One-stage versus quadrant-by-quadrant non-surgical periodontal therapy in type 2 diabetes

19.07.18

Patients with type 2 diabetes mellitus (T2DM) exhibit higher prevalence and severity of chronic periodontitis compared to individuals without diabetes.
Non-surgical periodontal therapy (NSPT), including scaling and root planing (SRP), has been suggested to improve glycaemic control in T2DM patients.

MicroRNA biomarkers for periodontitis with and without diabetes

15.05.18

This study investigated whether 2 microRNAs in gingival crevicular fluid could help identify periodontitis in people with and without type 2 diabetes. Both markers were elevated in periodontitis and decreased after non-surgical treatment, suggesting potential roles in disease assessment and monitoring treatment response.

Impact of glycaemic status on the subgingival microbiome in diabetes

09.05.18

The human microbiome plays a vital role in health, with links between gut microbiota and metabolic disorders like type 2 diabetes mellitus (T2DM).The oral microbiota, particularly the subgingival microbiome, is thought to be influenced by diabetes.

Green tea, periodontal blood vessels and diabetes-related bone loss

16.04.18

This animal study investigated whether green tea could protect periodontal tissues during prolonged hyperglycaemia in rats with type 1 diabetes. Green tea consumption preserved measures of the small blood vessel network and reduced periodontal destruction, although it did not completely prevent disease.

Periodontal disease and gestational diabetes: a prospective cohort study

03.04.18

Gestational diabetes mellitus (GDM) is a carbohydrate intolerance which begins during pregnancy, with Indian women at significantly higher risk (approximately 11-fold) compared to Caucasians.

Analysis of systemic inflammation on the link between periodontitis and glycaemic status

03.03.18

• Emerging evidence suggests that periodontitis may increase the risk of developing type 2 diabetes.
• Cross-sectional studies, such as NHANES III in the US and KNHANES in Korea, have shown that periodontitis is associated with impaired fasting glucose and diabetes.
• Prospective studies in the US, Germany, and Japan further confirmed that individuals with periodontitis have poorer glycaemic control and higher risk of diabetes.

Periodontitis and retinal vessel health

31.01.18

Chronic periodontitis is a common inflammatory disease that causes progressive bone loss and, if untreated, can lead to tooth loss.

Osteocyte signalling and periodontal bone loss in diabetes

25.01.18

This experimental study investigated how osteocytes (cells embedded within bone) contribute to periodontal bone loss in mice with and without diabetes. Deleting their production of RANKL (a signal that promotes bone breakdown) prevented significant infection-induced bone loss in both groups.

Diabetes, smoking and inhibitors of periodontal bone formation

12.01.18

This human study investigated whether diabetes and smoking were associated with increased levels of proteins that inhibit bone formation in people with periodontitis. Both risk factors were linked to changes in sclerostin and DKK1, suggesting a possible mechanism through which periodontal bone maintenance and repair may be impaired.

Periodontal condition and type 2 diabetes risk: 15-year follow-up results

22.08.18

Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterised by insulin resistance and elevated blood glucose levels, influenced by factors like obesity and inflammation.

One-stage versus quadrant-by-quadrant non-surgical periodontal therapy in type 2 diabetes

19.07.18

Patients with type 2 diabetes mellitus (T2DM) exhibit higher prevalence and severity of chronic periodontitis compared to individuals without diabetes.
Non-surgical periodontal therapy (NSPT), including scaling and root planing (SRP), has been suggested to improve glycaemic control in T2DM patients.

MicroRNA biomarkers for periodontitis with and without diabetes

15.05.18

This study investigated whether 2 microRNAs in gingival crevicular fluid could help identify periodontitis in people with and without type 2 diabetes. Both markers were elevated in periodontitis and decreased after non-surgical treatment, suggesting potential roles in disease assessment and monitoring treatment response.

Impact of glycaemic status on the subgingival microbiome in diabetes

09.05.18

The human microbiome plays a vital role in health, with links between gut microbiota and metabolic disorders like type 2 diabetes mellitus (T2DM).The oral microbiota, particularly the subgingival microbiome, is thought to be influenced by diabetes.

Green tea, periodontal blood vessels and diabetes-related bone loss

16.04.18

This animal study investigated whether green tea could protect periodontal tissues during prolonged hyperglycaemia in rats with type 1 diabetes. Green tea consumption preserved measures of the small blood vessel network and reduced periodontal destruction, although it did not completely prevent disease.

Periodontal disease and gestational diabetes: a prospective cohort study

03.04.18

Gestational diabetes mellitus (GDM) is a carbohydrate intolerance which begins during pregnancy, with Indian women at significantly higher risk (approximately 11-fold) compared to Caucasians.

Analysis of systemic inflammation on the link between periodontitis and glycaemic status

03.03.18

• Emerging evidence suggests that periodontitis may increase the risk of developing type 2 diabetes.
• Cross-sectional studies, such as NHANES III in the US and KNHANES in Korea, have shown that periodontitis is associated with impaired fasting glucose and diabetes.
• Prospective studies in the US, Germany, and Japan further confirmed that individuals with periodontitis have poorer glycaemic control and higher risk of diabetes.

Periodontitis and retinal vessel health

31.01.18

Chronic periodontitis is a common inflammatory disease that causes progressive bone loss and, if untreated, can lead to tooth loss.

Osteocyte signalling and periodontal bone loss in diabetes

25.01.18

This experimental study investigated how osteocytes (cells embedded within bone) contribute to periodontal bone loss in mice with and without diabetes. Deleting their production of RANKL (a signal that promotes bone breakdown) prevented significant infection-induced bone loss in both groups.

Diabetes, smoking and inhibitors of periodontal bone formation

12.01.18

This human study investigated whether diabetes and smoking were associated with increased levels of proteins that inhibit bone formation in people with periodontitis. Both risk factors were linked to changes in sclerostin and DKK1, suggesting a possible mechanism through which periodontal bone maintenance and repair may be impaired.