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Research Hub

Welcome to the Research Hub – your go-to source for concise, digestible summaries of the latest research on the connection between periodontitis and diabetes. Explore key findings on topics such as how periodontal inflammation affects glycaemic control and the benefits of periodontal treatment.

Our summaries provide quick insights, but they are not exhaustive. For a complete understanding of each study’s methodology, results, and implications, we encourage you to review the original research articles. Please note that the Periodontitis-Diabetes hub is not responsible for inaccuracies or misinterpretations of condensed content.

For more guidance on understanding research, including how to interpret studies and evaluate their findings, visit the ‘Colgate Professional Website’ and search for ‘Understanding Research in Dentistry.’

Dive into the science and uncover the powerful link between oral and systemic health!

Featured posts

Treating periodontitis can help improve blood sugar control in people with diabetes

14.04.22

Diabetes mellitus (DM) is a chronic condition where the body fails to produce or effectively use insulin, resulting in elevated blood glucose. Poor glycaemic control in DM patients can lead to severe complications like cardiovascular disease and kidney failure. The glycosylated haemoglobin assay (HbA1c) is a reliable measure of long-term blood sugar control and is linked to the risk of diabetic complications.

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Periodontitis and diabetes risk in Hispanic/Latino adults

02.02.22

  • Periodontitis (gum disease) is an inflammatory condition linked to systemic diseases like diabetes.
  • Hispanic/Latino adults in the U.S. face a high prevalence of both periodontitis and diabetes, but the link between gum disease and the development of diabetes or prediabetes in this population remains unclear.
  • This study aimed to investigate whether gum disease severity influences the risk of developing prediabetes or diabetes over six years in a large cohort of Hispanic/Latino adults.
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The use of periodontal measures for diabetes screening

23.01.22

Diabetes mellitus (DM) is a significant global health issue, often remaining undiagnosed during its asymptomatic phase. Timely detection can prevent complications. Given the bidirectional link between diabetes and periodontitis, dental professionals are uniquely positioned to identify undiagnosed hyperglycaemia using periodontal measures.

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Development of gestational diabetes in pregnant women with periodontitis

14.12.21

Periodontitis is a chronic inflammatory disease leading to the destruction of tooth-supporting tissues and eventual tooth loss if untreated. It is highly prevalent worldwide, affecting 10–60% of populations. Beyond oral health, periodontitis contributes to systemic diseases by allowing pathogens (bacteria) and inflammatory mediators to enter the circulatory system, increasing risks for conditions like diabetes mellitus (DM), cardiovascular diseases, and adverse pregnancy outcomes.

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Patient and tooth-related factors in the loss of molars in maintenance

14.12.21

Tooth loss (TL), a significant outcome of periodontitis, affects patients physiologically and psychologically. Periodontal therapy and patient compliance during supportive periodontal care (SPC) are crucial in reducing TL risk.Studies highlight patient- and tooth-related factors influencing TL, including periodontal bone loss, tooth mobility, furcation involvement (FI), tooth type, and vitality, with FI identified as a major predictor of molar survival.

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Periodontal disease and treatment response linked to sudden onset diabetes risk

03.10.21

Periodontitis (gum disease) is a chronic inflammatory condition affecting the tissues that support teeth. It has been associated with systemic conditions like cardiovascular disease and diabetes.

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Metabolic risk factors in young adults with gum disease

03.10.21

Periodontitis is a chronic inflammatory condition that causes gum and bone damage. It is often linked with systemic inflammation and conditions like metabolic syndrome (MetS).

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Inflammatory cell death exaggerates periodontal inflamm-ageing

18.08.21

Diabetes mellitus (DM) accelerates periodontal disease through hyperglycaemia-induced inflamm-ageing, a chronic, low-grade inflammatory state driven by cellular senescence and the senescence-associated secretory phenotype (SASP). Inflamm-aging disrupts gingival defence mechanisms, including epithelial and fibroblast resistance and immune responses to infection.

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Predictors of tooth loss during periodontal maintenance

17.05.21

Periodontal maintenance (PM) is crucial for preventing the progression of periodontitis and minimising tooth loss after active periodontal treatment (APT). It includes tailored care such as oral hygiene education, scaling, root planing, and tooth polishing. Despite advances in periodontal therapy, factors like age, smoking, diabetes, and compliance with PM visits impact treatment outcomes.

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Tailored periodontal maintenance preserves teeth in high-risk cases

16.05.21

Periodontitis is a chronic inflammatory disease causing tissue destruction and tooth loss, often requiring lifelong management. Regular maintenance, termed supportive periodontal therapy (SPT), plays a crucial role in preventing disease progression. The World Workshop (2017) introduced a multidimensional classification for periodontitis, categorising cases into stages (severity) and grades (rate of progression). This study aims to evaluate how the regularity of maintenance visits impacts tooth loss related to periodontitis (TLP) based on staging and grading. It hypothesises that higher disease severity (stages III/IV) and rapid progression (grade C) increase susceptibility to tooth loss, especially with inconsistent maintenance.

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Periodontitis is the 6th most prevalent condition globally

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Periodontitis and diabetes are bidirectionally linked

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Diabetic complications are increased if you have both diseases

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Successful periodontal treatment can improve blood glucose control

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Periodontitis is the 6th most prevalent condition globally

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Periodontitis and diabetes are bidirectionally linked

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Diabetic complications are increased if you have both diseases

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Successful periodontal treatment can improve blood glucose control

Our Team

Team - The Periodontitis-Diabetes Hub

Dr Varkha Rattu

Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Education & Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Outreach & Communications Lead

Team - The Periodontitis-Diabetes Hub

Dr Varkha Rattu

Periodontitis-Diabetes Hub Position: Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Periodontitis-Diabetes Hub Position: Education and Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Periodontitis-Diabetes Hub Position: Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Periodontitis-Diabetes Hub Position: Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Periodontitis-Diabetes Hub Position: Outreach and Communications Lead

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