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Research Hub

Welcome to the Research Hub – your go-to source for concise, digestible summaries of the latest research on the connection between periodontitis and diabetes. Explore key findings on topics such as how periodontal inflammation affects glycaemic control and the benefits of periodontal treatment.

Our summaries provide quick insights, but they are not exhaustive. For a complete understanding of each study’s methodology, results, and implications, we encourage you to review the original research articles. Please note that the Periodontitis-Diabetes hub is not responsible for inaccuracies or misinterpretations of condensed content.

For more guidance on understanding research, including how to interpret studies and evaluate their findings, visit the ‘Colgate Professional Website’  and search for ‘Understanding Research in Dentistry.’

Dive into the science and uncover the powerful link between oral and systemic health!

Featured posts

Dental visits may help identify people who need diabetes testing

12.11.24

Type 2 diabetes mellitus (T2DM) is a growing global health issue, with millions remaining undiagnosed.In Singapore, diabetes prevalence is among the highest in Southeast Asia, with half of those affected unaware of their condition at diagnosis.

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Tiny particles in gum fluid may help explain pregnancy-related diabetes links

12.11.24

In 104 pregnant women, extracellular vesicles (EVs — tiny membrane-wrapped particles released by cells and bacteria that carry proteins and other molecules) collected from the gum crevice were more abundant, and had a distinctive surface-marker profile, in women with both periodontitis and gestational diabetes mellitus (GDM). Their protein cargo pointed to roles in immune inflammation, glucose metabolism and insulin response, and included virulence factors from periodontal bacteria – supporting the idea that gum-derived EVs may biologically link periodontitis and GDM.

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Eating patterns and the bacteria living beneath the gums

12.10.24

Higher dietary quality was associated with differences in subgingival bacterial diversity and a more favourable balance of disease-associated to health-associated bacteria. These observational findings suggest a possible link between diet and the periodontal microbiome, rather than demonstrating a treatment effect.

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Gum disease and later heart-related health problems

11.09.24

Periodontitis was associated with a higher incidence of cardiovascular events or death over approximately 10 years, after adjustment for age, smoking and diabetes.

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Mouth bacteria and long-term health: what variety may tell us

16.08.24

A study of more than 8,000 adults found a link between the variety of bacteria in mouth-rinse samples and long-term health. It does not show that changing mouth bacteria will extend life or that a probiotic or mouthwash provides this benefit.

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Why diabetes may worsen inflammation around implants: a mouse study

12.08.24

Some people with diabetes experience problems with the tissues around dental implants. Mice with diabetes and implant inflammation lost more supporting bone than mice with inflammation alone.

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Heart-health measures and gum health often go together

04.07.24

Health behaviours and medical measurements are often considered together when assessing cardiovascular health. People with higher overall scores were less likely to have periodontitis and tended to have less severe gum damage.

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Gum disease and long-term health: what is the link?

27.05.24

Periodontitis affects up to 45% of adults in the United States (US) and has been significantly associated with various systemic health conditions such as diabetes and cardiovascular disease. Current research suggests that periodontal disease may not only impact oral health but also influence overall mortality.

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Sugary drinks and gum disease: an observed link

07.03.24

Many people think about sugar in relation to tooth decay or blood glucose. This study asked a different question – whether drinking sugary drinks more often was linked to disease affecting the tissues that support the teeth.

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Gum health improved during intensive diabetes care

06.03.24

Diabetes and gum health may influence each other. Average HbA1c fell from 9.6% to 7.4%.

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Periodontitis is the 6th most prevalent condition globally

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Periodontitis and diabetes are bidirectionally linked

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Diabetic complications are increased if you have both diseases

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Successful periodontal treatment can improve blood glucose control

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Periodontitis is the 6th most prevalent condition globally

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Periodontitis and diabetes are bidirectionally linked

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Diabetic complications are increased if you have both diseases

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Successful periodontal treatment can improve blood glucose control

Our Team

Team - The Periodontitis-Diabetes Hub

Dr Varkha Rattu

Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Education & Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Outreach & Communications Lead

Team - The Periodontitis-Diabetes Hub

Dr Varkha Rattu

Periodontitis-Diabetes Hub Position: Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Periodontitis-Diabetes Hub Position: Education and Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Periodontitis-Diabetes Hub Position: Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Periodontitis-Diabetes Hub Position: Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Periodontitis-Diabetes Hub Position: Outreach and Communications Lead

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