Research

Insulin resistance and gum disease: the role of shared factors

10.11.10

Insulin resistance and gum disease can occur alongside other health factors, including changes in body weight. Before all adjustments, higher insulin resistance showed a weak relationship with very deep pockets, and some associations were stronger in younger adults.

Gum healing and immune signals at different glucose levels

28.09.10

People can experience improved gum health even when blood glucose remains above target. Both groups showed substantial reductions in plaque, bleeding and pocket depth.

Gum disease, blood pressure and heart measurements in diabetes

12.07.10

Diabetes, high blood pressure and gum disease may occur together. Participants with periodontitis had higher blood pressure and greater left ventricular mass than those with healthier gums.

Blood glucose and worsening gum disease over time

14.05.10

Following people over time can help identify factors associated with worsening gum disease. Higher HbA1c was associated with greater odds of worsening pocket depth and loss of tooth support.

Gum health and type 2 diabetes in an urban Sri Lankan study

07.01.10

Diabetes and gum disease may be associated differently across populations. People with diabetes had more gum bleeding and recession.

Gum treatment improved oral health without a clear glucose change

14.12.09

Dental treatment can be successful even when blood glucose does not improve. Plaque, bleeding, pocket depth and measurements of tooth support improved.

Type 1 diabetes and the response to plaque build-up

14.12.09

Gingivitis is inflammation of the gums caused by plaque build-up. Both groups developed more inflammation during plaque build-up.

Is there a connection between insulin resistance and periodontitis in a non-diabetic population?

10.11.10

Insulin resistance, a condition where cells fail to respond effectively to insulin, is central to metabolic disorders like type 2 diabetes and cardiovascular disease. It often leads to systemic low-grade inflammation, a feature shared with periodontal disease, suggesting a potential biological link between these conditions.

Cytokine levels in periodontitis among type 2 diabetes patients

28.09.10

Periodontitis and diabetes share a bidirectional relationship, where poor glycaemic control exacerbates periodontal disease and vice versa. The interplay between periodontal inflammation and glycaemic status is mediated by immune cells, primarily T-helper (Th) cells, which regulate pro- and anti-inflammatory cytokine production.

Periodontitis, blood pressure, and cardiovascular risk in people living with type 2 diabetes

12.07.10

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Periodontal progression and glycaemic control in Gullah African Americans

14.05.10

Periodontal disease and type 2 diabetes mellitus (T2DM) are interrelated, with evidence suggesting that periodontal disease worsens diabetic control and, conversely, that managing periodontal disease can improve glycaemic control. The host inflammatory response plays a key role in increasing susceptibility to periodontal disease, particularly in individuals with systemic conditions like T2DM. Studies show that individuals with severe periodontitis experience more diabetes-related complications and have poorer HbA1c levels over time. The Gullah population of coastal South Carolina and Georgia, descendants of enslaved Africans, is particularly affected by T2DM due to their genetic predisposition and social isolation. The Gullah have a higher prevalence of chronic diseases, including obesity and hypertension, compared to other populations. Notably, periodontal disease is more prevalent among Gullah individuals with T2DM (70.6%) compared to national estimates for African Americans with diabetes (31.3%). This study aimed to explore the relationship between glycaemic control and periodontal disease progression in Gullah individuals with T2DM.

Periodontal health in urban Sri Lankans with type 2 diabetes

07.01.10

Diabetes poses a significant public health burden globally, with prevalence expected to rise sharply, especially in urbanizing areas of developing countries.

Impact of periodontal treatment on metabolic control and inflammation in type 2 diabetes

14.12.09

Periodontitis, an inflammatory disease causing tissue destruction of the tissues surrounding teeth, may influence systemic inflammation, particularly in individuals with diabetes.

Biomarkers and gum health in type 1 diabetes

14.12.09

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.