Research

Does antiseptic treatment add to full-mouth cleaning?

07.11.12

Full-mouth periodontal cleaning can be combined with antiseptic products in an approach sometimes called full-mouth disinfection. Gum bleeding, pocket depth and the support around teeth improved in both groups.

Saliva signals of gum inflammation and type 2 diabetes

15.02.12

Saliva contains substances released during inflammation. Both diabetes and periodontitis were associated with higher beta-glucuronidase levels, with periodontal disease showing the stronger relationship.

Treating persistent gum pockets in type 2 diabetes

30.01.12

Some gum pockets remain deep and bleed after initial periodontal treatment. Both approaches reduced pocket depth, bleeding and the number of persistent pockets.

Diabetes and chemical stress in inflamed gums: a rat study

26.01.12

The immune response produces reactive chemicals that help defend against infection. Rats with diabetes showed more inflammatory activity and bone loss around affected teeth.

Type 1 diabetes and gum health in adults who do not smoke

31.10.11

Smoking can strongly influence gum health, making it harder to separate its effects from those of diabetes. On average, participants with type 1 diabetes had worse gum measurements, particularly those with higher HbA1c.

An enzyme that may link high glucose with gum damage

20.10.11

Enzymes help remodel tissues, but excessive activity during inflammation can contribute to damage. MMP-8 expression was greatest in tissue from people with both diabetes and periodontitis, and was higher than in those with periodontitis alone.

HDL cholesterol and gum inflammation in type 1 diabetes

09.10.11

Cholesterol measurements are usually discussed in relation to heart health. Higher HDL levels were associated with fewer inflamed, deep-pocket sites.

Oxidative stress when diabetes and gum disease occur together

24.08.11

Oxidative stress happens when reactive chemicals outweigh the body’s protective systems. Participants with both conditions showed more protein oxidation and lower antioxidant capacity than some comparison groups.

Inflammation and gum healing in type 1 diabetes

19.04.11

Gum treatment can improve local inflammation without changing every inflammatory marker in the blood. Gum health improved, but average blood levels of inflammatory markers, including IL-6, did not change significantly.

Gum treatment and blood glucose improvement over six months

29.11.10

Periodontal treatment aims to control gum disease. The treated group had greater improvements in gum bleeding, pocket depth and tooth support.

Full-mouth disinfection for diabetes patients with chronic periodontitis

07.11.12

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Inflammatory biomarkers in patients living with periodontitis

15.02.12

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Surgical and non-surgical therapy with antimicrobials for residual pockets in type 2 diabetes

30.01.12

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Nitrosative stress in experimental periodontitis in diabetic rats

26.01.12

Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth, leading to progressive periodontal tissue destruction and eventual tooth loss if untreated. The main aetiological factor for periodontitis is plaque. However, the two main risk factors for progression of the disease have been identified as smoking and diabetes.

How periodontitis affects non-smoking adults with type 1 diabetes

31.10.11

Type 1 Diabetes Mellitus (T1DM) is associated with systemic inflammation, which may worsen oral health. Periodontitis, a chronic inflammatory condition leading to gum and bone loss, has been linked to worse glycaemic control.

Elevated enzyme activity in periodontitis and diabetes

20.10.11

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Cholesterol levels and periodontal inflammation in type 1 diabetes

09.10.11

Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth, leading to progressive periodontal tissue destruction and eventual tooth loss if untreated. The main aetiological factor for periodontitis is plaque. However, the two main risk factors for progression of the disease have been identified as smoking and diabetes.

Oxidative stress and inflammatory status in type 2 diabetes with periodontitis

24.08.11

Periodontitis is a chronic inflammatory disease affecting tooth-supporting tissues, driven by pathogenic plaque biofilm and a hyper-inflammatory host response. It leads to periodontal pocket formation, tissue destruction, and potential tooth loss. Individuals with Type 2 diabetes face an increased risk and severity of periodontitis due to their predisposition to oxidative stress and inflammation.

The role of inflammatory mediators in periodontal inflammation in type 1 diabetes

19.04.11

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Periodontal treatment on diabetes care

29.11.10

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.