Research

Gum disease and tiny retinal blood vessels in diabetes

07.04.15

Small blood vessels at the back of the eye can be measured from photographs. Severe periodontitis was associated with slightly wider retinal venules, the small vessels that carry blood away.

Pre-diabetes was not consistently linked to gum disease in this study

13.03.15

Studies do not all find the same relationship between early glucose abnormalities and gum disease. After adjustment, prediabetes was not consistently associated with periodontitis or tooth loss.

Nutrition, blood glucose and gum bone loss in rural Java

12.02.15

Nutrition and access to care may affect both general and dental health. More bone loss was associated with higher levels of one periodontal bacterium and a blood inflammation marker.

What happens after a dental visit identifies raised blood glucose?

28.01.15

Finding a raised screening result only helps if people can access appropriate follow-up. Many participants in both groups reported seeing a physician.

Body weight and response to gum treatment: evidence remains uncertain

09.01.15

Patients may hear that body weight affects healing and wonder whether periodontal treatment will work for them. The review did not identify a consistent, clear difference in the main periodontal treatment outcomes between weight groups.

A growth factor helped bone healing in diabetic rats

05.12.14

Diabetes can impair healing after tissue injury. The growth factor increased new bone volume and thickness and increased the number of dividing cells.

Dental findings in people with previously unrecognised high glucose

11.10.14

Raised blood glucose can be present before a person receives a diagnosis. People with results in the diabetes range had more gum bleeding, deeper pockets and more missing teeth than those with lower glucose results.

Doxycycline offered little extra benefit in a diabetes gum-treatment trial

09.07.14

Antibiotics are sometimes added to gum cleaning, but the extra benefit needs to be demonstrated. Both groups’ gums improved.

Can antibiotics add to gum treatment in type 2 diabetes?

13.06.14

Cleaning below the gumline is used to treat periodontitis, a disease that damages the tissues supporting teeth. Both groups improved.

Gum treatment improved oral health, but glucose benefits were uncertain

05.05.14

People with diabetes may wonder whether treating gum disease can also lower blood glucose. Professional treatment produced clearer improvements in gum pocket depth, bleeding and the support around teeth than education alone.

Periodontitis and retinal blood vessel changes in diabetes

07.04.15

Severe periodontitis was associated with wider retinal venules (the small vessels carrying blood away from the retina). The association was significant in participants with diabetes, but not in those without diabetes.

Pre-diabetes and periodontitis – is there a link?

21.03.15

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Nutrition, pre-diabetes and periodontal bone loss in rural Java

12.02.15

This study examined the relationship between periodontal bone loss, nutrition, blood glucose and inflammation in an Indonesian population with limited access to dental care. Greater bone loss was associated with higher levels of periodontal bacteria and systemic inflammation, alongside lower body mass index and less frequent guava consumption. No significant association with HbA1c was identified.

Dental patients identified with hyperglycaemia

28.01.15

Diabetes mellitus (DM) is a significant global health challenge, with Type 2 diabete mellitus (T2DM) often going undiagnosed for years. It is estimated that 46% of diabetes cases worldwide remain undiagnosed, contributing to delayed treatment and increased complications.

The effect of obesity on the success of periodontal treatment

09.01.15

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

FGF-2 improves periodontal healing in diabetic rats through cell proliferation and blood-vessel maturation

05.12.14

In rats with newly induced diabetes, surgically created periodontal defects healed poorly. A single application of fibroblast growth factor-2 (FGF-2 – a signalling protein that drives cell growth and blood-vessel formation) mixed with a carrier gel produced more new bone, thicker bone trabeculae (the fine internal beams of spongy bone), less unwanted downgrowth of gum epithelium into the defect, and better-quality blood vessels. However, it did not restore new cementum, indicating that a single dose is not enough for full periodontal regeneration in diabetes.

Periodontal findings in newly diagnosed individuals with pre-diabetes or diabetes

11.10.14

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Evaluating the role of doxycycline in managing periodontitis in people living with type 2 diabetes

09.07.14

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Antibiotics alongside non-surgical therapy in patients with type 2 diabetes

13.06.14

Diabetes mellitus (DM) is a common condition linked to systemic and oral complications, including periodontitis, with evidence of a bidirectional relationship between the two.

Non-surgical periodontal treatment on diabetes management

05.05.14

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.