Acute-phase response following one-stage full-mouth versus quadrant non-surgical periodontal treatment in subjects with comorbid type 2 diabetes: A randomised clinical trial.
(Journal of Clinical Periodontology; doi: 10.1111/jcpe.13760)
Filippo Graziani, Stefano Gennai, Crystal Marruganti, Marina Peric, Lorenzo Ghiadoni, Urska Marhl, Morena Petrini
Cleaning below the gumline can be completed in one longer session or over several appointments. Researchers asked whether the schedule affected short-term inflammation and later outcomes in people with type 2 diabetes.
Forty people with diabetes and periodontitis were randomly allocated to full-mouth treatment in one session or treatment spread across three weeks. Researchers assessed inflammation shortly afterwards and gum health, blood glucose and quality of life at three months.
Both schedules improved gum health, with no clear difference in the main dental improvements. The one-session group had a larger rise in inflammation markers and a temporary change in a blood-vessel measurement the next day. The staged-treatment group had a greater HbA1c improvement at three months, but this came from a small trial.
The findings suggest that appointment scheduling can affect the body’s immediate response, but they do not prove that one long visit causes a serious medical event. Blood markers and blood-vessel measurements are not the same as clinical complications. Choosing a schedule should consider your medical history, treatment needs and practical circumstances. This study alone is not enough to establish one approach as best for everyone with diabetes.
The most useful comparison is the difference between the treatment groups, rather than improvement within just one group. Results also depend on who took part, the comparison care and how long people were followed. A statistically uncertain difference does not prove two approaches are identical. Equally, a clear difference in a measurement may not show a lasting benefit for tooth retention or general health. These findings need to be considered alongside other trials and your individual clinical needs when discussing treatment choices.
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Periodontitis is the 6th most prevalent condition globally
Periodontitis and diabetes are bidirectionally linked
Diabetic complications are increased if you have both diseases
Successful periodontal treatment can improve blood glucose control
Periodontitis is the 6th most prevalent condition globally
Periodontitis and diabetes are bidirectionally linked
Diabetic complications are increased if you have both diseases
Successful periodontal treatment can improve blood glucose control
