Tooth survival and clinical outcomes up to 26 years after guided tissue regeneration therapy in deep intra-bony defects: Follow-up investigation of three randomized clinical trials
(Journal of Clinical Periodontology; doi: 10.1111/jcpe.13302)
Fabian Cieplik, Insa Ihlenfeld, Karl-Anton Hiller, Andreas Pummer, Gottfried Schmalz, Wolfgang Buchalla, Michael Christgau
Regenerative surgery aims to help rebuild support around selected teeth with deep periodontal defects. This study revisited patients many years after a procedure using a barrier membrane to guide healing.
Researchers followed participants from earlier surgical trials for up to twenty-six years. Information was available for fifty patients, although only thirty-four had a new clinical examination. The analysis focused on tooth retention rather than reliably comparing the original membrane types.
Around half of the studied teeth remained after this very long follow-up. Retained teeth often maintained improvements in support gained during the first year. Molars, deeper initial defects and less favourable early healing were associated with tooth loss. Diabetes and smoking history also appeared relevant, but the remaining sample was small.
A tooth with a deep defect may remain useful for many years after treatment, but surgery cannot guarantee lifetime survival. The selected defects in this study are not the same as every tooth affected by periodontitis. Nor does eventual tooth loss necessarily mean that the earlier years of function had no value. An individual decision should weigh likely benefit, treatment burden, alternatives and the ongoing care the tooth would need.
Following people over time helps researchers study the order of events, but it does not remove all uncertainty. People with different health or dental histories may also differ in medicines, smoking, access to care and other influences. Some participants may be missing from later assessments. Statistical adjustments cannot fully account for everything. The results describe patterns in the people studied, not a personal forecast. They should be considered alongside other research and your own clinical findings when discussing their relevance to you.
Read the full article Back to ResearchHosted by #diabeteschat, join Dr Varkha Rattu and the team behind the Periodontitis-Diabetes Hub for an insightful discussion exploring the importance of managing periodontitis and diabetes.
Read moreDr Antoniszczak will present a lecture about the oral health challenges among people living with diabetes. This lecture explores the key challenges faced by individuals living with diabetes, focusing on…
Read moreHosted by #diabeteschat, join Dr Varkha Rattu and the team behind the Periodontitis-Diabetes Hub for an insightful discussion exploring the importance of managing periodontitis and diabetes.
Read moreDr Antoniszczak will present a lecture about the oral health challenges among people living with diabetes. This lecture explores the key challenges faced by individuals living with diabetes, focusing on the relationship between diabetes and oral health.
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