Gum treatment responses with and without diabetes

Summarised from:

Clinical and microbiological effects of scaling and root planing, metronidazole and amoxicillin in the treatment of diabetic and non‐diabetic subjects with periodontitis: A cohort study.
(Journal of Clinical Periodontology; doi: 10.1111/jcpe.12994)

Authors:

Poliana Mendes Duarte, Magda Feres, Lina Lameh Smeili Yassine, Geisla Mary Silva Soares, Tamires Szeremeske Miranda, Marcelo Faveri, Belen Retamal-Valdes, Luciene Cristina Figueiredo

Summarised by:

Dr Dominika Antoniszczak

Research Topic:

Why does this matter?

People with diabetes may worry that gum treatment will be less effective for them. This analysis compared responses to a combined treatment programme in patients with severe periodontitis.

What was studied?

Researchers brought together data from earlier trials for fifty-eight people, half with diabetes and half without. Everyone received cleaning below the gumline, two antibiotics and maintenance care. Outcomes were compared over twelve months.

What did the researchers find?

Both groups experienced substantial improvements. Roughly three-quarters of the diabetes group and two-thirds of the comparison group reached the study’s gum-pocket target. Some measures of support gain and bacterial reduction were more favourable without diabetes, but the overall findings showed that people with diabetes could respond well. The sample was small and excluded some medically complex patients.

What does this mean for me?

The study is reassuring about the possibility of successful treatment, but it does not establish that everyone with diabetes needs antibiotics. Because all participants received them, this comparison cannot show how much benefit they added to cleaning. Treatment choices need to account for the condition of your gums, medical circumstances and the advantages and disadvantages of additional medicines. Diabetes alone should not be used to assume either treatment failure or a need for the same drug regimen.

What should I keep in mind?

Following people over time helps researchers study the order of events, but it does not remove all uncertainty. People with different health or dental histories may also differ in medicines, smoking, access to care and other influences. Some participants may be missing from later assessments. Statistical adjustments cannot fully account for everything. The results describe patterns in the people studied, not a personal forecast. They should be considered alongside other research and your own clinical findings when discussing their relevance to you.

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Research  |  21.10.18

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