Effect of periodontal treatment on glycated haemoglobin and metabolic syndrome parameters: A randomized clinical trial.
(Journal of Clinical Periodontology; doi: 10.1111/jcpe.13717)
Fernanda C Milanesi, Bruna F Greggianin, Gabriela O dos Santos, Mirian P Toniazzo, Patricia Weidlich, Fernando Gerchman, Rui V Oppermann
Metabolic syndrome combines several risks, such as raised glucose, blood pressure and changes in blood fats or waist size. Researchers tested whether treating gum disease would improve these medical measurements.
A Brazilian trial randomly assigned 158 people with metabolic syndrome and moderate-to-severe periodontitis to gum treatment or delayed dental treatment. Both groups continued medical care. Follow-up measurements were taken over six months.
Gum treatment substantially improved plaque, bleeding and deep gum pockets. However, the treated and comparison groups did not show clear differences in HbA1c, blood pressure, blood fats, waist size or the other metabolic and inflammation measurements assessed. Metabolic syndrome was not more likely to resolve in the gum-treatment group.
This is useful evidence even though the medical outcomes did not improve. Treating periodontitis can be worthwhile for dental health without producing a measurable change in every aspect of general health. The trial does not support presenting gum treatment as a way to reverse metabolic syndrome. Participants had relatively well-managed, recently diagnosed metabolic syndrome, so results may differ in other groups, but any wider benefit needs to be demonstrated rather than assumed.
The most useful comparison is the difference between the treatment groups, rather than improvement within just one group. Results also depend on who took part, the comparison care and how long people were followed. A statistically uncertain difference does not prove two approaches are identical. Equally, a clear difference in a measurement may not show a lasting benefit for tooth retention or general health. These findings need to be considered alongside other trials and your individual clinical needs when discussing treatment choices.
Read the full article Back to ResearchHosted by #diabeteschat, join Dr Varkha Rattu and the team behind the Periodontitis-Diabetes Hub for an insightful discussion exploring the importance of managing periodontitis and diabetes.
Read moreDr Antoniszczak will present a lecture about the oral health challenges among people living with diabetes. This lecture explores the key challenges faced by individuals living with diabetes, focusing on…
Read moreHosted by #diabeteschat, join Dr Varkha Rattu and the team behind the Periodontitis-Diabetes Hub for an insightful discussion exploring the importance of managing periodontitis and diabetes.
Read moreDr Antoniszczak will present a lecture about the oral health challenges among people living with diabetes. This lecture explores the key challenges faced by individuals living with diabetes, focusing on the relationship between diabetes and oral health.
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