A randomized, controlled trial on the effect of non-surgical periodontal therapy in patients with type 2 diabetes. Part I: effect on periodontal status and glycaemic control
(Journal of Clinical Periodontology; doi: 10.1111/j.1600-051X.2010.01652.x)
Panagiotis A. Koromantzos, Konstantinos Makrilakis, Xanthippi Dereka, Nicholas Katsilambros, Ioannis A. Vrotsos, Phoebus N. Madianos
Periodontal treatment aims to control gum disease. Researchers have also tested whether reducing this inflammation can help blood glucose management in people with type 2 diabetes.
Sixty adults with type 2 diabetes and moderate-to-severe periodontitis were randomly assigned to treatment or delayed treatment. The treatment group received cleaning below the gums and further periodontal support when needed. Researchers measured gum health and HbA1c over six months. HbA1c reflects average blood glucose over recent months rather than a single day’s reading.
The treated group had greater improvements in gum bleeding, pocket depth and tooth support. Average HbA1c fell by 0.72 percentage points in this group compared with 0.13 percentage points in the comparison group, with a statistically clear difference. Seven participants did not complete follow-up; the analysis used their last available measurements. That approach preserves participants in the analysis but relies on assumptions about their later outcomes.
This trial supports a possible glucose benefit alongside improved gum health. The average change is not a guarantee of the result an individual will experience. It also does not show that periodontal care can replace diabetes medicines or prevent long-term diabetes complications. Gum treatment and diabetes management should be considered complementary parts of care, with outcomes monitored by the relevant clinical teams.
The most useful comparison is the difference between the treatment groups, rather than improvement within just one group. Results also depend on who took part, the comparison care and how long people were followed. A statistically uncertain difference does not prove two approaches are identical. Equally, a clear difference in a measurement may not show a lasting benefit for tooth retention or general health. These findings need to be considered alongside other trials and your individual clinical needs when discussing treatment choices.
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Periodontitis is the 6th most prevalent condition globally
Periodontitis and diabetes are bidirectionally linked
Diabetic complications are increased if you have both diseases
Successful periodontal treatment can improve blood glucose control
Periodontitis is the 6th most prevalent condition globally
Periodontitis and diabetes are bidirectionally linked
Diabetic complications are increased if you have both diseases
Successful periodontal treatment can improve blood glucose control
