Gum treatment and a heart-function measurement in type 2 diabetes

Summarised from:

A randomized controlled trial of the effects of non-surgical periodontal therapy on cardiac function assessed by echocardiography in type 2 diabetic patients

(Journal of Clinical Periodontology; doi: 10.1111/jcpe.13291)

Authors:

Yi Wang, Hin Nam Liu, Zhe Zhen, George Pelekos, Mei Zhen Wu, Yan Chen, Maurizio Tonetti, Hung Fat Tse, Kai Hang Yiu, Lijian Jin

Summarised by:

Dr Varkha Rattu

Research Topic:

Why does this matter?

Researchers are exploring whether reducing gum inflammation affects the heart as well as the mouth. This small trial examined a heart ultrasound measurement in people with type 2 diabetes and periodontitis.

What was studied?

Fifty-eight people were randomly assigned to non-surgical gum treatment or oral hygiene advice alone. Researchers assessed dental health, blood tests and heart ultrasound findings over six months. Fifty-five had the necessary follow-up information for analysis.

What did the researchers find?

Gum health improved with treatment. One ultrasound measure related to how the heart relaxes and fills also improved, but other heart measurements did not clearly change. There were no clear between-group improvements in HbA1c or the measured inflammation markers. The trial did not measure a reduction in heart attacks, heart failure admissions or deaths.

What does this mean for me?

The result is a reason for further research, not evidence that gum treatment is a treatment for heart disease. A change in an ultrasound number may or may not translate into a benefit a patient notices. Dental treatment can still be valuable for the gums even when blood glucose is unchanged. People with heart or diabetes concerns should continue their medical assessment alongside dental care rather than interpreting this study as a replacement pathway.

What should I keep in mind?

The most useful comparison is the difference between the treatment groups, rather than improvement within just one group. Results also depend on who took part, the comparison care and how long people were followed. A statistically uncertain difference does not prove two approaches are identical. Equally, a clear difference in a measurement may not show a lasting benefit for tooth retention or general health. These findings need to be considered alongside other trials and your individual clinical needs when discussing treatment choices.

Read the full article Back to Research

Research  |  29.04.20

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Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

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Professor Mark Ide

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

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Professor Luigi Nibali

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Periodontitis-Diabetes Hub Position: Patient Resource Advisor

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