Early gum disease did not clearly predict higher blood sugar later

Summarised from:

Periodontitis is not associated with metabolic risk during the fourth decade of life
(Journal of Clinical Periodontology; doi: 10.1111/jcpe.12641)

Authors:

Dara M Shearer, W Murray Thomson, Jonathan M Broadbent, Jim Mann, Richie Poulton

Summarised by:

Dr Varkha Rattu

Research Topic:

Why does this matter?

Researchers wanted to understand whether gum disease in young adulthood predicts later changes in blood glucose. This study followed people before the ages when type 2 diabetes commonly becomes more frequent.

What was studied?

The Dunedin birth cohort in New Zealand was assessed at ages twenty-six, thirty-two and thirty-eight. Researchers grouped people by their HbA1c patterns over time and compared these with gum findings, allowing for smoking, social circumstances and abdominal body size.

What did the researchers find?

Periodontitis at twenty-six did not clearly predict membership of the highest HbA1c group after adjustment. Some later gum findings were associated with very small glucose differences. Those statistical groupings were not diagnoses of diabetes, and an alternative measure of average gum support loss showed no association.

What does this mean for me?

This study does not show that early gum disease causes diabetes. It also illustrates that a statistically detectable change can be too small to have an obvious practical meaning for an individual. Follow-up ended at thirty-eight, so later-life outcomes remain uncertain. Gum disease should still be assessed for its effects on teeth, while concern about diabetes risk should be addressed through the usual medical assessment rather than inferred from these research groups.

What should I keep in mind?

Following people over time helps researchers study the order of events, but it does not remove all uncertainty. People with different health or dental histories may also differ in medicines, smoking, access to care and other influences. Some participants may be missing from later assessments. Statistical adjustments cannot fully account for everything. The results describe patterns in the people studied, not a personal forecast. They should be considered alongside other research and your own clinical findings when discussing their relevance to you.

Read the full article Back to Research

Research  |  04.07.19

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Periodontitis-Diabetes Hub Position: Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Periodontitis-Diabetes Hub Position: Education and Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Periodontitis-Diabetes Hub Position: Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Periodontitis-Diabetes Hub Position: Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Periodontitis-Diabetes Hub Position: Outreach and Communications Lead

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