Effect of subgingival periodontal therapy on glycaemic control in type 2 diabetes patients: Meta-analysis and meta-regression of 6-month follow-up randomised clinical trials.
(Journal of Clinical Periodontology; doi: 10.1111/jcpe.13830)
Victor Bento Oliveira, Fábio Wildson Gurgel Costa, Alex Nogueira Haas, Renan Magalhães Montenegro Júnior, Rodrigo Otávio Rêgo
Periodontal treatment removes deposits from below the gumline to manage inflammation. This review examined whether that treatment, without added antimicrobial medicines, also changes blood glucose in people with type 2 diabetes.
Researchers reviewed twelve randomised trials, with eleven contributing to the combined numerical analysis. In total, 1,374 participants were included in that analysis. Outcomes were assessed at six months, focusing on HbA1c, a measure of average blood glucose.
HbA1c was approximately 0.29 percentage points lower in the treatment groups than in the comparison groups. This suggests a modest average benefit. All included studies had important risks of bias, however, and differences in treatment and disease definitions made comparisons less straightforward. The review did not show how long the effect would last beyond the follow-up studied.
Gum treatment may contribute to glucose management while addressing a dental condition that needs care in its own right. The average change should not be treated as a promise for an individual or as equivalent to starting a particular diabetes medicine. The evidence concerns people with both type 2 diabetes and periodontitis, rather than people with healthy gums. Your diabetes treatment should continue to be assessed on its own clinical needs.
A review can bring together more evidence than one study, but its conclusions still depend on the quality of the research included. Differences in participants, measurements and follow-up can make results difficult to combine. An average finding may not describe every patient, and an uncertain result does not prove there is no effect. This review also reflects the evidence available when its search ended. It should be read as one part of the evidence, with newer research considered before making current treatment decisions.
Read the full article Back to ResearchHosted by #diabeteschat, join Dr Varkha Rattu and the team behind the Periodontitis-Diabetes Hub for an insightful discussion exploring the importance of managing periodontitis and diabetes.
Read moreDr Antoniszczak will present a lecture about the oral health challenges among people living with diabetes. This lecture explores the key challenges faced by individuals living with diabetes, focusing on…
Read moreHosted by #diabeteschat, join Dr Varkha Rattu and the team behind the Periodontitis-Diabetes Hub for an insightful discussion exploring the importance of managing periodontitis and diabetes.
Read moreDr Antoniszczak will present a lecture about the oral health challenges among people living with diabetes. This lecture explores the key challenges faced by individuals living with diabetes, focusing on the relationship between diabetes and oral health.
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