Cleaning below the gums may modestly improve blood glucose

Summarised from:

Effect of subgingival periodontal therapy on glycaemic control in type 2 diabetes patients: Meta-analysis and meta-regression of 6-month follow-up randomised clinical trials.
(Journal of Clinical Periodontology; doi: 10.1111/jcpe.13830)

Authors:

Victor Bento Oliveira, Fábio Wildson Gurgel Costa, Alex Nogueira Haas, Renan Magalhães Montenegro Júnior, Rodrigo Otávio Rêgo

Summarised by:

Dr Mira Shah

Research Topic:

Why does this matter?

Periodontal treatment removes deposits from below the gumline to manage inflammation. This review examined whether that treatment, without added antimicrobial medicines, also changes blood glucose in people with type 2 diabetes.

What was studied?

Researchers reviewed twelve randomised trials, with eleven contributing to the combined numerical analysis. In total, 1,374 participants were included in that analysis. Outcomes were assessed at six months, focusing on HbA1c, a measure of average blood glucose.

What did the researchers find?

HbA1c was approximately 0.29 percentage points lower in the treatment groups than in the comparison groups. This suggests a modest average benefit. All included studies had important risks of bias, however, and differences in treatment and disease definitions made comparisons less straightforward. The review did not show how long the effect would last beyond the follow-up studied.

What does this mean for me?

Gum treatment may contribute to glucose management while addressing a dental condition that needs care in its own right. The average change should not be treated as a promise for an individual or as equivalent to starting a particular diabetes medicine. The evidence concerns people with both type 2 diabetes and periodontitis, rather than people with healthy gums. Your diabetes treatment should continue to be assessed on its own clinical needs.

What should I keep in mind?

A review can bring together more evidence than one study, but its conclusions still depend on the quality of the research included. Differences in participants, measurements and follow-up can make results difficult to combine. An average finding may not describe every patient, and an uncertain result does not prove there is no effect. This review also reflects the evidence available when its search ended. It should be read as one part of the evidence, with newer research considered before making current treatment decisions.

Read the full article Back to Research

Research  |  31.05.23

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